Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product name:Rebeprazole sodium |
Other Name: Rebeprazole sodium Salt |
Appearance:White powder |
CAS:117976-90-6 |
M.F.:C18H20N3NaO3S |
M.W.:381.42 |
Specification:99% |
Rabeprazole is a white to yellowish white powder, odorless, and its molecular weight is 381.43. This product is easily soluble in water or meth anol, soluble in absolute etha nol or eth yl ace tate, and almost insoluble in et her or et hane. This product does not show optical rotation, but has a thermo-absorption property. Its melting point is 225°C, and its distribution coefficient in a water/octane system with a pH of 7.0 is about 214.
ITEM | SPECIFICATION | RESULT | METHOD |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Rebeprazole sodium is an active pharmaceutical ingredient used to treat duodenal ulcers and erosive or gastroesophageal reflux disease .