| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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| Product name: Tianeptine Sulfate |
| Other Name:Tianeptina;Tianeptinum;COAXIL;Tianeptina [inn-spanish];Tianeotine |
| Appearance:White Powder |
| CAS NO.: 1224690-84-9 |
| M.F.: C42H56Cl2N4O14S3 |
| M.W.: 1008.01344 |
| Specification:99% |
Tianeptine is antidepressant. The animal has the hippocampus pyramidal cells increased spontaneousactivity, and accelerating its function was inhibited after recovery; increase in cortical and hippocampalneurons at sites of5- serotonin reuptake. Tianeptine without following adverse effects: sleep and alertness;cardiovascular system; cholinergic system ( without anticholinergic symptoms ); drug craving.
| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Tianeptine Sulfate not only a good antidepressant effect and adverse reactions was significantly less than conventional antidepressant tricyclic drugs, almost no adverse effect on the cardiovascular system, blood , liver and kidney functions were not hurt, nor do I have a calming effect. Tianeptine is not only effective for depression and depressive neurosis, chronic alcoholism and depression after alcohol is also effective. Long-term use can prevent relapse
It mainly acts on the 5-HT system, without excitement, sedation, anti-acetylcholine and cardiac toxicity. Used for depression
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