Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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High Quality API 99% Powder Antipyrine
Antipyrine is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic.
Phenazone, also known as phenazon, antipyrine, or analgesine, is an analgesic, a non-steroidal anti-inflammatory drug and an antipyretic. It was first synthesized by Ludwig Knorr in 1883. It is formed by reducing diortho- dinitrodiphenyl with sodium amalgam and methyl alcohol, or by heating diphenylene-ortho-dihydrazine with hydrochloric acid to 150 °C. It crystallizes in needles which melt at 156 °C. Potassium permanganate oxidizes it to pyridazine tetracarboxylic acid. Phenazone has an elimination half life of about 12 hours.
Product Name | Antipyrine/Phenazone |
Synonyms | 1,2-Dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one; 2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; Phenazone |
CAS No. | 60-80-0 |
EINECS | 200-486-6 |
Molecular Formula | C11H12N2O |
Molecular Weight | 188.23 |
Appearance | Colorless powder |
Melting point | 109-113 ºC |
Assay | 99% |
Item |
Standard |
Results |
Characteristics |
Colorless or white crystal |
conforms |
Melting Point |
110-113°C |
110.1-111.2°C |
Identification |
Positive |
Positive |
Chloride |
Not more than 100ppm |
conforms |
Sulphate |
Not more than 100ppm |
Conforms |
Sulphated Ash |
Not more than 0.1% |
Conforms |
Heavy Metals |
Not More than 20ppm |
<20ppm |
Colour of solution |
Conforms |
Conforms |
Acidic or Alkalinic Substances |
Conforms |
Conforms |
Loss on Drying |
Not more than 1.0% |
0.2% |
Assay(On dry basis) |
99.0-100.5% |
99.7% |
Conclusion |
Complies with BP2004 |