| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
|---|
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Lincomycin hydrochloride is used for semi-synthetic preparation of clindamycin. It is a semi-synthetic chlorinated derivative of lincomycin. It is suitable for various infectious diseases caused by gram-positive bacteria and anaerobic bacteria. It is used to treat infections caused by methicillin-resistant Staphylococcus aureus.
|
Product Name
|
Lincomycin HCl |
|
CAS
|
859-18-7 |
|
Appearance
|
White crystalline powder |
|
MF
|
C18H35ClN2O6S |
|
Molecular Weight
|
443 |
|
Purity
|
99%
|
|
Storage
|
Keep in a cool, dry, dark location in a tightly sealed container or cylinder
|
|
Shelf Life
|
24 Months
|
| Items | Standard |
| Appearance | A white or almost white, crystalline powder |
| Identification | The IR spectrum conforms to that obtained with the reference substance It solution gives reaction(a) of chlorides |
| Appearance of solution | Clear and not more intensely coloured than reference solution Y6 |
| pH | 3.5~5.5 |
| Specific optical rotation | +135°~+150° |
| Related substances | Related substances unspecified impurities≤0.1% Total impurities≤0.5% disregard limit≤0.05% |
| Heavy metals | ≤5ppm |
| Water | 5.5%~7.0% |
| Sulphated Ash | ≤0.1% |
| Bacterial endotoxins | ≤0.50IU/mg |
| Residual Solvent | N-butano≤5000ppm Octanol≤2ppm |
| Assay (On the anhydrous basis) It contains C18H35ClN2O6S |
Sum of the contents of lincomycin hydrochloride and lincomycin B hydrochloride:96.0%~102.0% Lincomycin B hydrochloride:≤5.0% |
Lincomycin hydrochloride is the product of the growth of Streptomyces lincolnensis (Streptomyces lincolnensis) flora. It is a kind of Lincosamides (Lincosamides) basic antibiotic. It acts on the 50S subunit of the ribosome of sensitive bacteria. Prevents the extension of the peptide chain, thereby inhibiting the protein synthesis of bacterial cells, with antibacterial effect, but also has a bactericidal effect on highly sensitive bacteria at high concentrations. The antibacterial spectrum is the same as lincomycin, but the antibacterial activity is stronger
Lincomycin hydrochloride has a strong antibacterial effect on Gram-positive bacteria, some anaerobic bacteria and mycoplasma, and its antibacterial spectrum is narrower than that of erythromycin. Staphylococcus aureus, hemolytic streptococcus, pneumococcus and Mycoplasma hyopneumoniae, Mycoplasma gallisepticum are sensitive to this product, but enterococci are generally resistant to this product; anaerobic bacteria such as Bacteroides, Tetanus, Clostridium, Clostridium weischii, Peptococcus, etc. are also sensitive to this product. It is mainly used to treat various infections caused by gram-positive bacteria, especially penicillin-resistant gram-positive bacteria, chronic respiratory diseases of poultry caused by mycoplasma, swine asthma, anaerobic infections such as necrotizing enteritis in chickens, etc. It is used to treat swine treponema dysentery, toxoplasmosis and actinomycosis in dogs and cats.
| Product Name | CAS NO. | Specification |
| Praziquantel | 55268-74-1 | 99% |
| Niclosamide | 50-65-7 | 99% |
| Lufenuron | 103055-07-8 | 99% |
| Ivermectin | 70288-86-7 | 99% |
| Eprinomectin | 123997-26-2 | 99% |
| Doramectin | 117704-25-3 | 99% |
| Avermectin | 71751-41-2 | 99% |
| Albendazole | 54965-21-8 | 99% |
| Levamisole Hydrochloride | 16595-80-5 | 99% |
| Fenpropathrin | 39515-41-8 | 99% |
| Bifenazate | 149877-41-8 | 99% |
| Chlorfluazuron | 71422-67-8 | 99% |
| Tetramisole Hydrochloride | 5086-74-8 | 99% |
| Fenbendazole | 43210-67-9 | 99% |
| Mebendazole | 31431-39-7 | 99% |
| Febantel | 58306-30-2 | 99% |
| Oxyclozanide | 2277-92-1 | 99% |
| Moxidectin | 113507-06-5 | 99% |
| Amprolium Hydrochloride | 137-88-2 | 99% |
| Toltrazuril | 69004-03-1 | 99% |
| pyrimethamine | 58-14-0 | 99% |
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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