Pharmaceutical Grade API Castration-Resistant Prostate Cancer Cabazitaxel Anti-Cancer Cabazitaxel

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Model NO.: Biohorlden-H001
• Product Name: Cabazitaxel Powder
• CAS: 183133-96-2
• Appearance: White Powder
• M.F.: C45h57no14
• M.W.: 835.93
• Shelf Life: 2 Years
• Storage: Room Temperature
• Grade: Medicine Grade
• Certificate: ISO/GMP
• Sample: Free Sample
• Transport Package: 10g/Bag; 100g/Bag; 1kg/Bag; 25kg/Bag
• Trademark: Biohorlden
• Origin: China
• HS Code: 29329990
• Production Capacity: 500kg/Month

Product Description

Product Description

Pharmaceutical Grade API Castration-Resistant Prostate Cancer Cabazitaxel Anti-Cancer Cabazitaxel

 

Product name:Cabazitaxel Powder

Other Name: Cabazitaxel; XRP-6258;TXD 258;7β,10β-Dimethoxydocetaxel

Appearance:White Powder

CAS:183133-96-2

M.F:C45H57NO14

M.W.:835.93

Specification:99%

 

Cabazitaxel (previously XRP-6258) is a semi-synthetic derivative of a natural taxoid. It was developed by Sanofi-Aventis and was approved by the U.S. FDA for the treatment of hormone-refractory prostate cancer on June 17, 2010. It is a microtubule inhibitor, and the fourth taxane to be approved as a cancer therapy.

Cabazitaxel in combination is a treatment option for hormone-refractory prostate cancer following docetaxel-based treatment.

Cabazitaxel anticancer mechanism and characteristics similar with docetaxel, belongs to anti-microtubule drugs. Cabazitaxel through binding to tubulin, promoting their assembly into microtubules, and can prevent these have assembled a microtubule disintegration of the stabilization of microtubules, thereby inhibiting cell mitosis, and interphase cellular functions (interphasecellularfunctions) of play.

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Detailed Photos

Specification

 

ITEM	SPECIFICATION	RESULT	METHOD
Appearance	White powder, neutral odor, highly hygroscopic	Conforms	Visual
Identification	Standard solution and test solution same spot,RF	Conforms	TLC
Specific Optical	-2.4°~ -2.8°	-2.72°
Heavy metals (as PB)	≤10ppm	Conforms	AAS
Sulfate (SO4)	≤0.02%	Conforms	Colorimetry
Chloride (Cl)	≤0.02%	Conforms	Colorimetry
Phosphate Ion (P)	≤5ppm	Conforms	Colorimetry
Residual solvent(ethanol)	≤1.0%	Conforms	HS-GC
pH	4.5~7.0	5.10
Related substance	Spot not bigger than standard solution spot	No spot	TLC
Water Content	≤2%	0.26%	KF
Assay (dried basis)	98.0%--102.0%	99.48%	Potentiometric titration
Assay (dried basis)	98.5%--100%	99.2%	HPLC

 

Function&Application

Function:

Cabazitaxel's anti-cancer mechanism and characteristics are similar to docetaxel and belong to anti-microtubule drugs. Cabazitaxel promotes its assembly into microtubules by binding to tubulin, while preventing the disassembly of these assembled microtubules, stabilizing microtubules, thereby inhibiting cell mitosis, and interphase cellular functions.

Company Profile

Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

Certifications

Packaging & Shipping

 

FAQ

Q1: Are you a manufacturer?

Answer: Yes, we are manufactuer.

 

Q2: Which kind of payment terms do you accept?

Standard terms: T/T, MoneyGram, Western Union, PayPal.

Also L/C at sight is acceptable for large amount.

 

Q3: Can you give me a discount price?

Sure,It depends on your qty.

 

Q4: How can i get a sample?

Free samples are available for some products,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

 

Q5: How to guarantee the Product Quality before placing orders?

Strict QC with 6 steps testing from raw material purchase to finished product.

 

Q6: How to solve the after-sale disputes?

First of all, our quality control will reduce the quality problem to near zero.

We accept Changing, Reshipping or Refunding service if any quality problem.