| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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Best Price High Purity Retinoic Acid Powder All-Trans-Retinoic Acid CAS 302-79-4
| Product name:Retinoic acid |
| Other Name:Tretinoin,Trans Retinoic Acid |
| Appearance:Yellow Powder |
| CAS:302-79-4 |
| M.F:C20H28O2 |
| M W:300.44 |
| Grade:Pharmaceutical Grade |
| Specification:99% |
Retinoic Acid/Tretinoin is the acid form of vitamin A and is also known as all-trans retinoic acid or ATRA. It is a drug commonly used to treat acne vulgaris and keratosis pilaris. It is available as a cream or gel It is also used to treat acute promyelocytic leukemia. It is also available as a generic.
Its success in treating acute promyelocytic leukemia was a major breakthrough in the treatment of this type of leukemia.It works in APL because the majority of cases involve a chromosomal translocation of chromosomes 15 and 17, which causes genetic fusion of the retinoic acid receptor gene to the promyelocytic leukemia gene.
This fusion PML-RAR protein is responsible for preventing immature myeloid cells from differentiating into more mature cells. This block in differentiation is thought to cause leukemia.
Related Product
| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | Yellow powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
1. Retinoic Acidis a drug commonly used to treat acne vulgaris and keratosis pilaris.
2. Retinoic Acid is available as a cream or gel. It is also used to treat acute promyelocytic leukemia.
3. Retinoic Acid can stimulate skin growth and keep epidermic normal.
4. Retinoic Acid can slow down skin aging process for solarization, remove tiny wrinkles.
5. Retinoic Acid can reduce skin roughness, so skin will become ruddy.
Application:
1. Retinoic Acid /Tretinoin is widely applied in pharmaceutical field, mainly used for the cure of dermatonosus like acne, ichthyosis and psoriasis abnormal, etc..
2. Retinoic Acid /Tretinoin can be made into tretinoin or retinoic acid cream to cureacne or other unhealthy skin.
3. Retinoic Acid/Tretinoin is used for skin keratinocytes-resistant drugs and cell-induced differentation drug.
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