| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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ISRIB (trans-isomer), the trans isomer of ISRIB, is a highly selective PERK inhibitor with an IC50 of 5 nM.
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Product Name
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ISRIB (trans-isomer) |
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CAS
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1597403-47-8 |
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Appearance
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White powder |
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MF
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C22H24Cl2N2O4 |
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Molecular Weight
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451.34 |
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Purity
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99%
|
|
Storage
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Keep in a cool, dry, dark location in a tightly sealed container or cylinder
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Shelf Life
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24 Months
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Description
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White to off-white powder
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White powder
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Solubility
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Freely soluble In water and methano and dichloromethan
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Complies
|
|
Identification
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(1)By IR, To match with working standard
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Complies
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|
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(2)It gives reaction of sodium
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Complies
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Impurities A
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≤0.1%
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Not detected
|
|
Related compounds
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Any impurity ≤0.1%
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<0.1%
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|
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Total impurities ≤0.4%
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Complies
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Residual Solvents
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Acetidi≤ 0.5%
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Complies
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Dichlorometha≤ 0.06%
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Complies
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|
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Methan≤ 0.3%
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Complies
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|
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Aceton ≤ 0.5%
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Complies
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|
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Acetonitri≤0.041%
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Not detected
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|
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Ethanol≤0.5%
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Complies
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|
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N, N-dimethylformamide N ≤0.088%
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Complies
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|
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Water
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≤ 5.0%
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Complies
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Assay
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99.0%-101.0%(On anhydrous basis)
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99.35%
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ISRIB has good pharmacokinetic characteristics and good bioavailability in vivo. Intraperitoneal injection (0.25 mg/kg) of ISRIB in mice increases long-term memory by enhancing spatial memory and fear memory.
| Name | CAS No. | Purity |
| Sunifiram | 314728-85-3 | 99.0% |
| Unifiram | 272786-64-8 | 99.0% |
| Idebenone | 58186-27-9 | 99.0% |
| Pramiracetam | 68497-62-1 | 99.0% |
| Fasoracetam | 110958-19-5 | 99.0% |
| Oxiracetam | 62613-82-5 | 99.0% |
| Phenylpiraceta hydrazide | 77472-71-0 | 99.0% |
| Galantamine Hydrobromide | 69353-21-5 | 98.0% |
| Tianeptine | 66981-73-5 | 99.0% |
| Tianeptine sodium | 30123-17-2 | 99.0% |
| Tianeptine hemisulfate monohydrate (THM) | 1224690-84-9 | 99.0% |
| 9-ME-BC(9-Methyl-9H-beta-carboline) | 2521/7/5 | 99.0% |
| Agomelatine | 138112-76-2 | 99.0% |
| 6-Paradol 98% | 27113-22-0 | 98% Oil form |
| 6-Paradol 50% | 27113-22-0 | 50% Powder form |
| Nicotinamide Riboside Chloride(NRC) | 23111-00-4 | 98.0% |
| Beta-Nicotinamide Mononucleotide(NMN) | 1094-61-7 | 99.0% |
| β-Nicotinamide Adenine Dinucleotide(NAD+) | 53-84-9 | 98.0% |
| Noopept,GVS-111 | 157115-85-0 | 99.0% |
| Piracetam | 7491-74-9 | 99.0% |
| Phenibut | 1078-21-3 | 99.0% |
| Coluracetam | 135463-81-9 | 99.0% |
| N-Methyl-D-aspartic acid(NMDA) | 6384-92-5 | 99.0% |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 99% Powder form |
| Alpha GPC(Choline Alfoscerate) | 28319-77-9 | 50% Graininess form |
| Citicoline | 987-78-0 | 99.0% |
| PRL-8-53 | 51352-87-5 | 98.0% |
| NSI-189 Phosphate | 1270138-41-4 | 99.0% |
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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