| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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Anti-Inflammatory Pharmaceutical Intermediate CAS 22204-53-1 API Naproxen Sodium Powder
Naproxen (English: Naproxen, INN), is a kind of NSAID, for normal or severe pain, fever,inflammation, and by rheumatoid arthritis, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, gout, menstrual cramps, tendonitis, slippery bursa phlogistic wait for disease caused by ankylosing reaction, also has therapeutic effect for menstrual disorders.
Product name: Naproxen
Synonyms: DL-Naproxen
CAS Registry Number: 22204-53-1
EINECS: 244-838-7
Molecular Formula: C14H14O3
Molecular Weight: 230.26
Appearance: White to light yellow crystal powder
Melting Point: 152-154 °C(lit.)
Refractive Index: 67.5 ° (C=1, CHCl3)
Storage Temp.: -20°C Freezer
Density: 1.197 g/cm3
| Item | Specifications | Results | |
| Appearance | White to almost white crystalline powder | Almost white crystalline |
|
| Identification | A. Infrared absorption | The infrared absorption spectrum is concordant with the reference spectrum |
Conform |
| B. Ultraviolet Absorption | Absorptivities at 272nm,calculated on the driedbase, do not differ by more than 3% |
<1% | |
| Specific rotation | -17.0°to -15.3° | -16.7° | |
| Loss on drying | ≤1.0% | 0.2% | |
| Heavy metals | ≤0.002% | <0.002% | |
| Free Naproxen | ≤1.0% | 0.1% | |
| Related substances (HPLC) | Impurity D(in-house) | ≤0.10% | <0.01% |
| Impurity E(in-house, Impurity C in EP) | ≤0.10% | <0.01% | |
| Any other impurity | ≤0.10% | <0.01% | |
| Total impurities | ≤0.5% | <0.01% | |
| Residual Solvents | ≤50ppm | <1ppm | |
| Methanol | ≤50ppm | <12ppm | |
| Ethanol | ≤100ppm | <8ppm | |
| [Assay] (On the dried basis) It contains C14H13NaO3 |
98.5% to 101.5% | 99.7% | |
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