| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
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Pharmaceutical Raw Material Capecitabine price CAS 154361-50-9 Raw powder 99% Purity Capecitabine
| Common Name | Capecitabine | ||
|---|---|---|---|
| CAS Number | 154361-50-9 | Molecular Weight | 359.350 |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 517.6±60.0 °C at 760 mmHg |
| Molecular Formula | C15H22FN3O6 | Melting Point | 110-121°C |
| MSDS | ChineseUSA | Flash Point | 266.8±32.9 °C |
| Item | Specification | Result |
| Appearance | white to off-white powder | Complies |
| Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
| Odor | Characteristic | Complies |
| Assay | 99% | 99.8% |
| Sieve analysis | 100% pass 80 mesh | Complies |
| Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
| Heavy Metal | <10ppm | Complies |
| As | <0.1ppm | 0.05ppm |
| Pb | <0.1ppm | 0.05ppm |
| Cd | <0.1ppm | 0.05ppm |
| Residual Solvents | <100ppm | Complies |
Capecitabine is an orally-administered chemotherapeutic agent used in the treatment of metastatic breast and colorectal cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumor, where it inhibits DNA synthesis and slows growth of tumor tissue.
Classification: Antineoplastic, antimetabolite Action/Kinetics: An oral prodrug of 5'-deoxy-5-fluorouridine (5'DFUR) that is converted to 5-fluorouracil (5-FU).
1.FdUMP and the folate cofactor, N5-10-methylenetetrahydrofolate, bind to thymidylate synthase to form a covalently bound ternary complex which inhibits the formation of thymidylate from uracil. Thymidylate is essential for the synthesis of DNA so a deficiency inhibits cell division.
2. nuclear transcriptional enzymes can mistakenly incorporate FUTP in place of uridine triphosphate during RNA synthesis; this interferes with RNA processing and protein synthesis.
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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