| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 230/kg
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
Cimetidine (brand name: Tagamet) is a kind of histamine H2 receptor antagonist being capable of inhibiting the production of stomach acid, which reduces the gastric volume and acidity. It is mainly used for the treatment of heartburn and peptic ulcers. There are also evidences that it can be used for the treatment of common warts, chronic calcific tendinitis of the shoulder, and even colorectal cancer. It is capable of not only inhibiting the gastric acid secretion, as well as pepsin and gastrins output, but also inhibiting the activity of cytochrome P450. It reduces the gastric acid secretion through binding to the H2 receptor locating on the basolateral membrane of the gastric parietal cell, and further blocking histamine effect.
|
Product Name
|
Cimetidine |
|
CAS
|
51481-61-9 |
|
Einecs No
|
257-232-2 |
|
Appearance
|
White crystalline powder
|
|
MF
|
C10H16N6S |
|
Molecular Weight
|
252.34 |
|
Purity
|
99%
|
|
Solubility
|
soluble in aceton, very slightly soluble in hot water and n-octanol, insoluble in cold water and methano.
|
|
Shelf Life
|
24 Months
|
| ltems | Specifications | Results | ||
| Appearance | White or yellowish-white crystalline powder, slightly hygroscopic |
Complies | ||
| Solubility | Practically insoluble in water, freely soluble in methylene chlorid, soluble in alcohol |
Complies | ||
| ldentification | IR | Corresponds with that of CRS standard | Complies | |
| HPLC | The retention time for HzBla and HB1 in chromatogram obtained with the best solution corresponds to those of standard preparation |
Complies | ||
| Appearance of solution | Clear and not more intensely colored than BYz | Complies | ||
| Specific optical rotation (anhydrous and solvent-free substance) |
-20~-17° | -17.7° | ||
| Related substances(%) | Individual impurities(BRT1.3-1.5)2.5 | L-1:<0.05 K:2.1 | ||
| Any other impurities≤1 | c:0.05 A:0.58 J:0.21 H:0.31 D:0.05F:<0.05 E:0.53-2:0.17 RTS1,09:0.08 |
|||
| Totals5 | 4 | |||
| Disregard limit:0.05 | ||||
| Ethanol and Formamide(%) |
Ethanol<5.0 | 3.9 | ||
| Formamides3.0 | 2.6 | |||
| Heavy metal(%) | s0.002 | <0.002 | ||
| Water(%) | ≤1.0 | 0.14 | ||
| Catalyst(ugg) | S1 | <1 | ||
| Sulphated ash(%) | ≤0.1 | 0.05 | ||
| Assay(%) (HPLC, on dry basis) |
HB13JH4aB1+H>B15) 290.9 | 98.1 | ||
| 95.gSHB4HB1a102.0 | 96 | |||
Used in the treatment of duodenal ulcer, gastric ulcer, upper gastrointestinal bleeding, chronic colitis, herpes zoster, disease such as chronic urticaria. Against the virus and immune enhancement have certain effect.
Related products| Product Name | CAS NO. | Specification |
| Praziquantel | 55268-74-1 | 99% |
| Niclosamide | 50-65-7 | 99% |
| Lufenuron | 103055-07-8 | 99% |
| Ivermectin | 70288-86-7 | 99% |
| Eprinomectin | 123997-26-2 | 99% |
| Doramectin | 117704-25-3 | 99% |
| Avermectin | 71751-41-2 | 99% |
| Albendazole | 54965-21-8 | 99% |
| Levamisole Hydrochloride | 16595-80-5 | 99% |
| Fenpropathrin | 39515-41-8 | 99% |
| Bifenazate | 149877-41-8 | 99% |
| Chlorfluazuron | 71422-67-8 | 99% |
| Tetramisole Hydrochloride | 5086-74-8 | 99% |
| Fenbendazole | 43210-67-9 | 99% |
| Mebendazole | 31431-39-7 | 99% |
| Febantel | 58306-30-2 | 99% |
| Oxyclozanide | 2277-92-1 | 99% |
| Moxidectin | 113507-06-5 | 99% |
| Amprolium Hydrochloride | 137-88-2 | 99% |
| Toltrazuril | 69004-03-1 | 99% |
| pyrimethamine | 58-14-0 | 99% |
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
){kind=link}