Powder: | Yes |
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Customized: | Non-Customized |
Certification: | GMP, ISO 9001, USP, BP |
Suitable for: | Elderly, Adult, Animal |
State: | Solid |
Purity: | >99% |
Samples: |
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Customization: |
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Pharmaceutical Grade High quality 99% powder Sofosbuvir 1190307-88-0 Raw powder low price Sofosbuvir
Common Name | Sofosbuvir | ||
---|---|---|---|
CAS Number | 1190307-88-0 | Molecular Weight | 529.453 |
Density | 1.4±0.1 g/cm3 | Boiling Point | N/A |
Molecular Formula | C22H29FN3O9P | Melting Point | N/A |
TEM
|
SPECIFICATION
|
METHOD REFERENCE
|
Appearance
|
white powder
|
Visual
|
Ammonium
|
≤200ppm
|
USPmonograph
|
Chloride
|
≤200ppm
|
USP35<221>
|
Sulfate
|
≤300ppm
|
USP35<221>
|
Iron
|
≤10ppm
|
USP35<241>
|
Arsenic
|
≤2ppm
|
USP35<211>
|
Heavy metals
|
≤10ppm
|
USP35<231>Method I
|
Loss on drying(3h at 105 ºC)
|
≤0.5%
|
USP35<731>
|
Residue on Ignition
|
≤0.1%
|
USP35<281>
|
Total impurities
|
≤2.0%
|
USP monograph
|
Assay(dry basis)
|
98.0% to 101.0%
|
USP monograph
|
Sofosbuvir is a new drug candidate for hepatitis C treatment, Previously known as PS-7977 or GS-7977, it has shown promising results in numerous in vitro studies against all the genotypes of HCV. It is a nucleotide analog that is a highly potent inhibitor of the NS5B polymerase in HCV.
Function
This drug has shown high efficacy in combination with several other drugs with and without PEG-INF, against HCV. Sofosbuvir is of special interest among the directly acting antiviral drugs under development, due to its high potency, low side effects, oral administration, and high barrier to resistance.
Application
Pramipexole dihydrochloride is a non-ergoline dopamine agonist indicated for treating early-stage Parkinson's disease (PD) andrestless legs syndrome (RLS). It is also sometimes used off-label as a treatment for cluster headache and to counteract the problems with sexual dysfunction experienced by some users of the selective serotonin reuptake inhibitor (SSRI) antidepressants. Pramipexole has shown robust effects on pilot studies in a placebo-controlled proof of concept study in bipolar disorder. It is also being investigated for the treatment of clinical depression and fibromyalgia.1190307-88-0
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