| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Hot Selling CAS 64-86-8 Colchicine Pharmaceutical Grade Colchicine Raw Powder Colchicin
| Product name: Colchicine |
| Other Name:Natural Colchicum Autumnale Extract |
| Appearance:Light Yellow powder |
| CAS:64-86-8 |
| M.F.:C22H25NO6 |
| M.W.:399.44 |
| Specification:99% |
Colchicine is an ancient remedy for the treatment of articular pain. Use of Colchicum alkaloid for the treatment of acute
gout occurred as early as 1810, and reports of its medicinal value exist from the first century AD. Colchicine is the
preferred agent in the treatment of acute gouty arthritis.
Colchicine treats joint pain and swelling due to gout. Colchicine also helps to prevent gout and gouty attacks. Colchicine
relieves pain and reduces the inflammation of acute gouty arthritis. Generic colchicine tablets are available.
| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | Light Yellow powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
1. It is anti-gout, anti-tumor, inhibiting the mitotic cell stopping in M phase.
2.It has the significant effects on breast cancer, cervical cancer, esophageal cancer,
lung cancer,gastric cancer and chronic myelogenous leukemia.
3.It also can be used for acute gout, anti-inflammatory analgesic.
4.In recent years ,furtherly expand its clinical application, for example:to
prevent atherosclerosis damage;to cure the liver cirrhosis; to relief the cycle
heat caused by abnormal catecholamine, the Behcet's disease;
the lumbar disc herniation,intractable waist pain and sciatica; prevent intestine adhesion.
5.In addition, its used as the treatment of Purple epilepsy caused thrombocytopenia;
Persistent apophysis erythema;Advanced schistosomiasis;
6.Moreover, using colchicine three can get the polyploidy,so Colchicine is indispensable in chromosome research.
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