Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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Pharmaceutical Grade High quality Temozolomide cas 85622-93-1 Fast Delivery Top Quality Temozolomide
Common Name | Temozolomide | ||
---|---|---|---|
CAS Number | 85622-93-1 | Molecular Weight | 194.151 |
Density | 2.0±0.1 g/cm3 | Boiling Point | 526.6±42.0 °C at 760 mmHg |
Molecular Formula | C6H6N6O2 | Melting Point | 212°C dec. |
MSDS | ChineseUSA | Flash Point | 272.3±27.9 °C |
Item | Specification | Result |
Appearance | white to off-white powder | Complies |
Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
Odor | Characteristic | Complies |
Assay | 99% | 99.8% |
Sieve analysis | 100% pass 80 mesh | Complies |
Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
Heavy Metal | <10ppm | Complies |
As | <0.1ppm | 0.05ppm |
Pb | <0.1ppm | 0.05ppm |
Cd | <0.1ppm | 0.05ppm |
Residual Solvents | <100ppm | Complies |
Temozolomide can be used in treatment of Grade IV astrocytoma. Methylation damages the DNA and triggers the death of tumor cells,temozolomide's ability to alkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions of guanine residues for the therapeutic benefit of temozolomide depends.
Temozolomide is an oral chemotherapy drug. It is an alkylating agent used as a treatment of some brain cancers; as a second-line treatment for astrocytoma and a first-line treatment for glioblastoma multiforme.
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