| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
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Natural Hair Loss Treatment Pure Way-316606 Powder 99% Way 316606
| Product name: WAY 316606 |
| Other Name:BenzenesulfonaMide, 5-(phenylsulfonyl)-N-4-piperidinyl-2-(trifluoroMethyl)- |
| Appearance:White Powder |
| CAS:915759-45-4 |
| M.F.:C18H19F3N2O4S2 |
| M.W.:448.48 |
| Specification:99% |
WAY 316606 WAY-316606 is a sFRP-1 (Secreted frizzled-related proteins) inhibitor (Ki=80 nM); an endogenous antagonist of the secreted glycoprotein Wnt. IC50 value: 80 nM (Kd); 0.65 uM (EC50)Target: sFRP-1 Research showed that WAY 316606 bound to sFRP-1 with a K(D) of 0.08 microM and inhibited it with an EC(50) of 0.65 microM. WAY 316606 increased total bone area in a murine calvarial org
| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
A compound originally developed to treat osteoporosis called way-316606 works by the same mechanism as CsA, specifically against SFRP1.When he treated hair follicles with way-316606, the unrelated drug was as effective as CsA in promoting hair growth.He suggests that applying way-316606 or similar compounds externally to the scalp of a bald person may promote hair growth to the same or better degree that can be achieved with CsA, without side effects.
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