Pharmaceutical Raw Material Antimalarial Pyrimethamine Powder CAS 58-14-0 Pyrimethamine

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: Biohorlden-H001
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Product Name: Pyrimethamine
• CAS: 58-14-0
• Appearance: White Powder
• M.F.: C12h13cln4
• M.W.: 248.71
• Shelf Life: 2 Years
• Storage: Room Temperature
• Grade: Medicine Grade
• Certificate: ISO/GMP
• Sample: Free Sample
• Transport Package: 10g/Bag; 100g/Bag; 1kg/Bag; 25kg/Bag
• Trademark: Biohorlden
• Origin: China
• HS Code: 2941906000
• Production Capacity: 500kg/Month

Product Description

Product Description

Pharmaceutical Raw Material Antimalarial Pyrimethamine Powder CAS 58-14-0 Pyrimethamine

 

Product name:Pyrimethamine

Other Name:Pyrimethamine

Appearance:White Powder

CAS:58-14-0

M.F:C12H13ClN4

M W:248.71

Grade:Pharmaceutical Grade

Specification:99%

 

Pyrimethamine  is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties. DHFR is a key enzyme in the redox cycle for production of tetrahydrofolate, a cofactor that is required for the synthesis of DNA and proteins.
This agent is often used in combination with other antimalarials for the treatment of uncomplicated falciparum malaria. Pyrimethamine is used with other medication (such as a sulfonamide) to treat a serious parasite infection (toxoplasmosis) of the body, brain, or eye or to prevent toxoplasmosis infection in people with HIV infection.

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Detailed Photos

Specification

tems	Standards	Results
Physical Analysis
Description	White Powder	Complies
Assay	99%	99.6%
Mesh Size	100 % pass 80 mesh	Complies
Ash	≤ 5.0%	2.85%
Loss on Drying	≤ 5.0%	2.65%
Chemical Analysis
Heavy Metal	≤ 10.0 mg/kg	Complies
Pb	≤ 2.0 mg/kg	Complies
As	≤ 1.0 mg/kg	Complies
Hg	≤ 0.1mg/kg	Complies
Microbiological Analysis
Residue of Pesticide	Negative	Negative
Total Plate Count	≤ 1000cfu/g	Complies
Yeast&Mold	≤ 100cfu/g	Complies
E.coil	Negative	Negative
Salmonella	Negative	Negative

 

Function&Application

Function:
Pyrimethamine (RP4753) can interfere with the synthesis of tetrahydrofolate by inhibiting dihydrofolate reductase (DHFR), which can act on protozoan infections.
This product can inhibit the dihydrofolate reductase of the plasmodium, thereby interfering with the normal generation of folic acid of the plasmodium. It is effective in the early stage of falciparum malaria and Plasmodium vivax erythrocytes. It is often used as a pathogenic preventive drug. In addition, it can also inhibit the development of malaria parasites in mosquitoes, so it can block transmission. It is clinically used to prevent malaria and anti-relapse treatment during resting period.

Company Profile

Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

Certifications

Packaging & Shipping

 

FAQ

Q1: Are you a manufacturer?

Answer: Yes, we are manufactuer.

 

Q2: Which kind of payment terms do you accept?

Standard terms: T/T, MoneyGram, Western Union, PayPal.

Also L/C at sight is acceptable for large amount.

 

Q3: Can you give me a discount price?

Sure,It depends on your qty.

 

Q4: How can i get a sample?

Free samples are available for some products,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

 

Q5: How to guarantee the Product Quality before placing orders?

Strict QC with 6 steps testing from raw material purchase to finished product.

 

Q6: How to solve the after-sale disputes?

First of all, our quality control will reduce the quality problem to near zero.

We accept Changing, Reshipping or Refunding service if any quality problem.