Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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Wholesale Purity 99% Doxycycline hydrochloride Doxycycline powder
Doxycycline is antibiotic medicine, tetracycline drugs, treatment for chlamydia mycoplasma infection. Its character is yellow or pale yellow crystalline powder, odor, taste bitter. Easily dissolved in water and methanol, slightly soluble in ethanol or acetone, insoluble in chloroform.
CAS no. : 10592-13-9
Molecular formula: C22H25ClN2O8
Molecular weight: 480.9
EINECS no. : 234-198-7
Melting point: 195-201 ºC
Flash point: 87 ºC
Storage conditions: 0-6°C
Solubility: H2O: 50 mg/mL, clear, yellow-green
Appearance: powder
Colors: yellow
Water solubility: Soluble in water.
Items
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Specifications
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Results
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Appearance
|
Yellow crystalline powder
|
Conforms
|
Identification
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TLC
|
Conforms
|
sulphuric acid reaction a yellow colour develops
|
Conforms
|
|
it gives reaction of chlorides
|
Conforms
|
|
PH
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2.0~3.0
|
2.3
|
Specific absorbance
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at 349nm e(1%) 300~355
|
320
|
Specific optical rotation
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-105 ~ -120°
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-110°
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Heavy metals:
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≤50ppm
|
< 20ppm
|
Light-absorbing impurities
|
at 490nm ≤0.07
|
0.03
|
Related substances
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6-epidoxycycline ≤2.0% metacycline ≤2.0% 4-epidoxycycline ≤0.5% (ep5) 4-epi-6-epidoxycycline ≤0.5% (ep5) oxytetracycline ≤0.5% (ep5) any other impurity ≤0.5% not identified impurities ≤0.1% (ep5) |
1.6% 0.1% Not found Not found Not found Not found Not found |
Ethanol
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4.3~6.0% (m/m)
|
4.5%
|
Sulphated ash
|
≤0.4%
|
0.05%
|
Water
|
1.4~2.8%
|
1.8%
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Assay
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95.0~102.0% ( c22h25cln2o8) based on anhydrous, ethanol-free substance |
98.6%
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Conclusion
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Conform with USP32
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