Factory Supply Good Price Nootropics Cdp-Choline Citicoline Raw Powder Citicoline Cdp-Choline

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: CDP-Choline Citicoline
• Transport Package: 1kg Per Bag, 25kg Per Drum
• Specification: 99%
• Trademark: Biohorlden
• Origin: China
• Production Capacity: 500kg/Month

Product Description

Product Description

 Nootropics raw powder Citicoline,CDP-choline

1) Name:Citicoline,CDP choline
2) Purity: >99%
3) Cas no.:987-78-0
4) Appearance: White powder
5) Supply Ability : 2Mt/Per Month
6) Storage: Store in a well-closed container away from moisture

 

 

CDP choline also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5'-diphosphocholine is an intermediate in the generation of phosphatidylcholine from choline, a common biochemical process in cell membranes. Citicoline is naturally occurring in the cells of human and animal tissue, in particular the organs.
 
CDP-choline is a nootropic compound that is essentially a prodrug for both choline and uridine, conferring both of those molecules to the body following oral ingestion of CDP-Choline. Specifically, the CDP-choline dissociates into choline and cytidine, with the cytidine then converting into uridine. CDP-choline is one of the three choline-containing phospholipids that can be orally supplemented (the other two being Alpha-GPC and phosphatidylcholine).
 
This supplement is catered towards preventing or treating memory impairments associated with aging due to the fact that both of the molecules it confers are neuroprotective and potentially enhance learning. While it appears to be more effective than phosphatidylcholine (PC) at this role, in part due to also increasing PC synthesis in the brain, its potency is somewhat comparable to that of Alpha-GPC.

 

 

Items	Specification
Appearance	White powder or cystalline powder, smell-less, soluble easily in water, insoluble in ethanol, chlorofom
Identification	1) Chemical reaction 2) The retention time of a major peak meets the requirements. 3) IR: consistent with the spectrum obtained with reference substance. 4) Show sodium flame
Acid value	6.0-7.5
Clarity and color of solution	Clarifying, colorless
Chlorides	≤0.05%
Ammonium	≤0.05%
Iron	≤0.01%
Phosphate	≤0.1%
Related substance
5'-CMP	≤0.3%
The other largest impurities	≤0.2%
The other total impurities	≤0.7%
Residual solvents
Loss on drying		≤6.0%
Heavy metals		≤5ppm
Arsenic		≤0.0001%
Endotoxin		≤0.3EU/mg

 



Memory Disorders

In a review of 14 clinical trials, the authors concluded there was evidence of benefit of citicoline on memory function and behaviour in patients suffering from cognitive deficits ranging from mild cognitive impairment to dementia. Dosing in most of the trials was 1000 mg/day. A more recent review reached the same conclusions, but went on to state that more clinical trials are needed to confirm its benefits.

Mechanism of Action

The neuroprotective effects exhibited by citicoline may be due to its preservation of cardiolipin and sphingomyelin, preservation of arachidonic acid content of phosphatidylcholine and phosphatidylethanolamine, partial restoration of phosphatidylcholine levels, and stimulation of glutathione synthesis and glutathione reductase activity.

Citicoline's effects may also be explained by the reduction of phospholipase A2 activity. Citicoline increases phosphatidylcholine synthesis. The mechanism for this may be: By converting 1, 2-diacylglycerol into phosphatidylcholine, stimulating the synthesis of SAMe, which aids in membrane stabilization and reduces levels of arachidonic acid. This is especially important after an ischemia, when arachidonic acid levels are elevated.

Dosage

Standard dosing of CDP-choline is to take 200-600mg in two divided doses usually separated by 8-12 hours, although a single daily dose is also sometimes used. There are some properties, such as attention-promotion or improving bioenergetics, that seem to respond exclusively or more strongly to the lower dosage range. Other properties like appetite are the opposite, and thus the ideal dosage depends somewhat on the goal.

Side Effects

Citicoline has a very low toxicity profile in animals and humans. Clinically, doses of 2000 mg per day have been observed and approved. Minor transient adverse effects are rare and most commonly include stomach pain and diarrhea.

 

 

 

 

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Packaging & Shipping

 

Company Profile

Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

 

 

Q1: How to confirm the Product Quality before placing orders?
A: By sending you our available samples.
Or if you have special requirement on the goods, we can prepare samples according to your requirement for your confirmation.
 
Q2: Can you supply free samples?
A: Yes, we can provide some free sample, but the shipping cost should be on the customers' account. You can either pay the shipping cost or arrange a courier to collect the samples.
 
Q3: What's the MOQ?
A: For the high value product, our MOQ starts from 1g and generally starts from 10g.
For other low value product, our MOQ starts from 100g and 1kg.
 
Q4: How to place order and make payment?
A: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by TradeManager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
 
Q5: How do you treat quality complaint?
A: All our products are strictly tested by our QC, and confirmed by QA; unqualified material will not be released to customer. 
In case any quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately.