| Powder: | Yes |
|---|---|
| Customized: | Non-Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
|---|
Suppliers with verified business licenses
Audited Supplier 
Manufacturer Supply high quality natural leech extract hirudin3 Hirudin Food additives Raw powder Hirudin
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roduct Name: |
Hirudin |
|
Cas No.: |
113274-56-9 |
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Appearance: |
Off white or brown powder(different specification with different color) |
|
Source: |
Leech |
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Solubility: |
Water soluble |
|
Specification: |
200~400Atu/g |
|
TEM
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SPECIFICATION
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METHOD REFERENCE
|
|
Appearance
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white powder
|
Visual
|
|
Ammonium
|
≤200ppm
|
USP
|
|
Chloride
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≤200ppm
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USP35<221>
|
|
Sulfate
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≤300ppm
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USP35<221>
|
|
Iron
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≤10ppm
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USP35<241>
|
|
Arsenic
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≤2ppm
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USP35<211>
|
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Heavy metals
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≤10ppm
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USP35<231>Method I
|
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Loss on drying(3h at 105 ºC)
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≤0.5%
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USP35<731>
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Residue on Ignition
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≤0.1%
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USP35<281>
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Total impurities
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≤2.0%
|
USP
|
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Assay(dry basis)
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98.0% to 101.0%
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USP
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Hirudin Powder is the most significant active constituents, is extracted from leech and its salivary glands, and is a kind of small molecule protein (polypeptide) which comprised of 65-66 amino acid.
Function
1.It is a naturally occurring peptide in the salivary glands of medicinal leeches (Hirudo medicinalis) that has a blood anticoagulant property.
2.Similar to antithrombin III, the anticoagulatant activity of hirudin powder is based on its ability to inhibit the pro-coagulant activity of thrombin.
3.It can prevent or dissolve the formation of clots and thrombi (i.e. it has a thrombolytic activity), and has therapeutic value in blood coagulation disorders, in the treatment of skin hematomas and of superficial varicose veins.
Application
1. Hirudin is a promising class of anticoagulation and anticonvulsant drugs that can be used to treat various thrombotic disorders, especially venous thrombosis and diffuse vascular coagulation;
2. It can also be used to prevent the formation of arterial thrombosis after surgery, prevent the formation of thrombus after thrombolysis or revascularization, and improve the extracorporeal blood circulation and hemodialysis.
3. In microsurgery, failure is often caused by vascular embolization at the anastomosis, and hirudin can promote wound healing. 4. Studies have also shown that hirudin can also play a role in the treatment of cancer. It can prevent the metastasis of tumor cells and has proven efficacy in tumors such as fibrosarcoma, osteosarcoma, angiosarcoma, melanoma, and leukemia.
4.Hirudin can also be combined with chemotherapy and radiation therapy to enhance efficacy due to the promotion of blood flow in tumors.
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Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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