Powder: | Yes |
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Customized: | Non-Customized |
Certification: | GMP, ISO 9001, USP, BP |
Suitable for: | Elderly, Children, Adult |
State: | Solid |
Purity: | >99% |
Samples: |
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Customization: |
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Common Name | Cyclophosphamide | ||
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CAS Number | 50-18-0 | Molecular Weight | 261.086 |
Density | 1.3±0.1 g/cm3 | Boiling Point | 336.1±52.0 °C at 760 mmHg |
Molecular Formula | C7H15Cl2N2O2P | Melting Point | 41-45ºC |
MSDS | N/A | Flash Point | 157.1±30.7 °C |
Item | Specification | Result |
Appearance | white to off-white powder | Complies |
Related substance (HPLC) | Total impurity ≤0.5% Max single impurity ≤0.1% |
0.2% 0.06% |
Odor | Characteristic | Complies |
Assay | 99% | 99.8% |
Sieve analysis | 100% pass 80 mesh | Complies |
Loss on Drying Residue on Ignition |
≤1.0% ≤1.0% |
0.12% 0.09% |
Heavy Metal | <10ppm | Complies |
As | <0.1ppm | 0.05ppm |
Pb | <0.1ppm | 0.05ppm |
Cd | <0.1ppm | 0.05ppm |
Residual Solvents | <100ppm | Complies |
Cyclophosphamide is a bifunctional alkylating agent and cell cycle non-specific drugs, can interfere with DNA and RNA function, especially in the former greater impact, it is cross-linked with DNA, inhibit DNA synthesis, the most obvious role in the S phase.
1.The product is the most commonly used alkylating agent antineoplastic drugs, into the body, the liver microsomal enzyme decomposition of the decomposition of the release of a strong alkylation of chloroethyl phosphate (or phosphoramide nitrogen mustard), and Tumor cells produce cytotoxic effect, in addition to this product also has significant immunosuppressive effect.
2.Clinical for malignant lymphoma, multiple myeloma, leukemia, breast cancer, ovarian cancer, cervical cancer, prostate cancer, colon cancer, bronchial cancer, lung cancer, have a certain effect. Can also be used for rheumatoid arthritis, nephrotic syndrome in children and the treatment of autoimmune diseases.
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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