Powder: | Yes |
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Customized: | Non-Customized |
Certification: | GMP, ISO 9001, USP, BP |
Suitable for: | Elderly, Adult, Animal |
State: | Solid |
Purity: | >99% |
Samples: |
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Customization: |
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Manufacturer Supply Food additives Lactoferrin price cas 112163-33-4 Food Grade Raw powder Lactoferrin
Common Name | Joro spider toxin | ||
---|---|---|---|
CAS Number | 112163-33-4 | Molecular Weight | 565.70500 |
Density | 1.195g/cm3 | Boiling Point | 979.9ºC at 760mmHg |
Molecular Formula | C27H47N7O6 | Melting Point | N/A |
MSDS | N/A | Flash Point | 546.4ºC |
Test items
|
Specifications
|
Test results
|
Appearance
|
Pink to reddish-brown powder
|
Pink powder
|
Protein,%
|
≥93.0%
|
94.0%
|
Assay of Lactoferrin in the total of protein ,%
|
≥95.0%
|
97.1%
|
Loss on drying,%
|
≤4.5%
|
4.12%
|
Ash ,%
|
≤1.5%
|
0.21%
|
Fe ,mg/100g
|
≤35
|
13.2
|
Solubility
|
Pass the test
|
Pass the test
|
PH
|
5.2-7.2
|
5.41
|
Pb ,mg/kg
|
≤1.0
|
Not detected (<0.05)
|
As, ,mg/kg
|
≤1.0
|
Not detected (<0.01)
|
Total plate account ,CFU/g
|
≤1000
|
<10
|
Mold and Yeast
|
≤10
|
0
|
Coliforms ,MPN/g
|
<3.0
|
<0.3
|
Salmonella ,/25g
|
Negative
|
Not detected
|
Staphylococcus aureus,/25g
|
Negative
|
Not detected
|
Conclusion :
|
Conform to the above specifications
|
Function
Lactoferrin belongs to the innate immune system. Apart from its main biological function, namely binding and transport of iron ions, lactoferrin also has antibacterial, antiviral, antiparasitic, catalytic, anti-cancer, and anti-allergic functions and properties.
Enzymatic activity of lactoferrin
Lactoferrin hydrolyzes RNA and exhibits the properties of pyrimidine-specific secretory ribonucleases. In particular, by destroying the RNA genome, milk RNase inhibits reverse transcription of retroviruses that cause breast cancer in mice. Parsi women in West India have the milk RNase level markedly lower than in other groups, and their breast cancer rate is three times higher than average. Thus, ribonucleases of milk, and lactoferrin in particular, might play an important role in pathogenesis of diseases caused by various retroviruses.
Lactoferrin receptor
The lactoferrin receptor plays an important role in the internalization of lactoferrin; it also facilitates absorption of iron ions by lactoferrin. It was shown that gene expression increases with age in the duodenum and decreases in the jejunum. The moonlighting glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH) has been demonstrated to function as a receptor for lactoferrin.
Bone activity
Ribonuclease-enriched lactoferrin has been used to examine how lactoferrin affects bone. Lactoferrin has shown to have positive effects on bone turnover. It has aided in decreasing bone resorption and increasing bone formation. This was indicated by a decrease in the levels of two bone resorption markers (deoxypyridinoline and N-telopeptide) and an increase in the levels two bone formation markers (osteocalcin and alkaline phosphatase). It has reduced osteoclast formation, which signifies a decrease in pro-inflammatory responses and an increase in anti-inflammatory responses which indicates a reduction in bone resorption as well.
Interaction with nucleic acids
One of the important properties of lactoferrin is its ability to bind with nucleic acids. The fraction of protein extracted from milk, contains 3.3% RNA, but, the protein preferably binds to double-stranded DNA rather than single-stranded DNA. The ability of lactoferrin to bind DNA is used for its isolation and purification using affinity chromatography with columns containing immobilized DNA-containing sorbents, such as agarose with the immobilized single-stranded DNA.
Application
Product Name | CAS No. | Product Name | CAS No. |
Lufenuron | 103055-07-8 | Toltrazuril | 69004-03-1 |
Nitenpyram | 120738-89-8 | Praziquantel/Biltricide | 55268-74-1 |
Fenbendazole | 43210-67-9 | Tetramisole Hcl | 5086-74-8 |
Levamisole | 14769-73-4 | Ponazuril | 9004-4-2 |
Diclazuril | 101831-37-2 | Florfenicol | 73231-34-2 |
Ivermectin | 70288-86-7 | Enrofloxacin Hcl | 112732-17-9 |
Albendazole | 54965-21-8 | Mebendazole | 31431-39-7 |
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