Pharmaceutical Grade High Quality 99% Powder Indomethacin 53-86-1 Raw Powder Low Price Purity 99% Indomethacin

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult, Animal
• State: Solid
• Purity: >99%
• Model NO.: Indomethacin
• Transport Package: 1kg Per Bag, 25kg Per Drum
• Specification: 99%
• Trademark: Biohorlden
• Origin: China
• Production Capacity: 50000kg/Month

Product Description

Product Description

Pharmaceutical Grade High quality 99% powder Indomethacin 53-86-1 Raw powder low price Purity 99% Indomethacin
 

ommon Name	Indometacin
CAS Number	53-86-1	Molecular Weight	357.78800
Density	1.32g/cm3	Boiling Point	499.4ºC at 760 mmHg
Molecular Formula	C19H16ClNO4	Melting Point	155-162 °C
MSDS	ChineseUSA	Flash Point	255.8ºC

 

TEM	SPECIFICATION	METHOD REFERENCE
Appearance	white powder	Visual
Ammonium	≤200ppm	USPmonograph
Chloride	≤200ppm	USP35<221>
Sulfate	≤300ppm	USP35<221>
Iron	≤10ppm	USP35<241>
Arsenic	≤2ppm	USP35<211>
Heavy metals	≤10ppm	USP35<231>Method I
Loss on drying(3h at 105 ºC)	≤0.5%	USP35<731>
Residue on Ignition	≤0.1%	USP35<281>
Total impurities	≤2.0%	USP monograph
Assay(dry basis)	98.0% to 101.0%	USP monograph

 

Indomethacin, an antiinflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

Function
This product has obvious effect on anti-inflammation and antipyretic, can be easily absorbed and excreted. It can be fully  absorbed after taken orally in the gastrointestinal tract,  and in 1-4 hours the  plasma concentration will reach a peak; it will be excreted by liver metabolism, with the urine. Analgesic effects on inflammatory pain there, and its mechanism of inhibiting prostaglandin synthesis. 


Application
Salicylic acid is mainly used on the efficacy of drugs difficult to tolerate, or not significant rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and so on. Can also be used for acute gout and cancer, fever, or other difficult to control fever.

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Packaging & Shipping

 

Company Profile

Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

1.Are you a manufacturer or trade company?

We are a professional manufacturer.

2.What's your payment terms?

Standard terms: T/T in advance and Western Union.

Also L/C at sight is acceptable for large amount.

3.What's your shipping time?

3-5 days

4.How do you ensure the quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

5.How do you ship the order normally?

By air, by sea. By express: DHL,FEDEX,UPS,TXT,EMS,and so on.

6.What's your loading port?

Usually Beijing, Shanghai, Qingdao, Tianjin, Guangzhou