| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
|
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Pharmaceutical Grade High quality 99% powder Indomethacin 53-86-1 Raw powder low price Purity 99% Indomethacin
| ommon Name | Indometacin | ||
|---|---|---|---|
| CAS Number | 53-86-1 | Molecular Weight | 357.78800 |
| Density | 1.32g/cm3 | Boiling Point | 499.4ºC at 760 mmHg |
| Molecular Formula | C19H16ClNO4 | Melting Point | 155-162 °C |
| MSDS | ChineseUSA | Flash Point | 255.8ºC |
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TEM
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SPECIFICATION
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METHOD REFERENCE
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Appearance
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white powder
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Visual
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Ammonium
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≤200ppm
|
USPmonograph
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Chloride
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≤200ppm
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USP35<221>
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|
Sulfate
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≤300ppm
|
USP35<221>
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|
Iron
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≤10ppm
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USP35<241>
|
|
Arsenic
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≤2ppm
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USP35<211>
|
|
Heavy metals
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≤10ppm
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USP35<231>Method I
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Loss on drying(3h at 105 ºC)
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≤0.5%
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USP35<731>
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Residue on Ignition
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≤0.1%
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USP35<281>
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Total impurities
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≤2.0%
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USP monograph
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Assay(dry basis)
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98.0% to 101.0%
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USP monograph
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Indomethacin, an antiinflammatory agent, inhibits Cox-1 and Cox-2 (cyclooxygenases) with selectivity for Cox-1 (IC50 of 230 nM) over Cox-2 (IC50 of 630 nM). Additionally, indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.
Function
This product has obvious effect on anti-inflammation and antipyretic, can be easily absorbed and excreted. It can be fully absorbed after taken orally in the gastrointestinal tract, and in 1-4 hours the plasma concentration will reach a peak; it will be excreted by liver metabolism, with the urine. Analgesic effects on inflammatory pain there, and its mechanism of inhibiting prostaglandin synthesis.
Application
Salicylic acid is mainly used on the efficacy of drugs difficult to tolerate, or not significant rheumatoid arthritis, ankylosing spondylitis, osteoarthritis and so on. Can also be used for acute gout and cancer, fever, or other difficult to control fever.
| Product Name | CAS No. | Product Name | CAS No. |
| Lufenuron | 103055-07-8 | Toltrazuril | 69004-03-1 |
| Nitenpyram | 120738-89-8 | Praziquantel/Biltricide | 55268-74-1 |
| Fenbendazole | 43210-67-9 | Tetramisole Hcl | 5086-74-8 |
| Levamisole | 14769-73-4 | Ponazuril | 9004-4-2 |
| Diclazuril | 101831-37-2 | Florfenicol | 73231-34-2 |
| Ivermectin | 70288-86-7 | Enrofloxacin Hcl | 112732-17-9 |
| Albendazole | 54965-21-8 | Mebendazole | 31431-39-7 |
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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