Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Non-Customized |
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Cefoperazone sodium is the sodium salt of cefoperazone, which is the third generation cephalosporin, and has good antibacterial effect on e. coli, klebsiella, proteus, salmonella typhimurium, shigella, citrate and other enterobacteriaceae bacteria and pseudomonas aeruginosa.
ITEM
|
STANDARD
|
RESULTS
|
Appearance
|
White or almost white crystalline granule and powder
|
A white crystalline granule and powder
|
Identification
|
(1) The spectrum obtained with the substance to be examined corresponds with that obtained with reference standard (2) Should meet the requirement under water |
Conforms
|
Appearance of solution
|
≤reference suspension II (1 mol/L hydrochloric acid) ≤reference suspension II (2 mol/L ammonia) |
≤Reference suspension I ≤Reference suspension I |
PH
|
3.5~5.5
|
4.4
|
Specific optical rotation
|
+280~ +305
|
+296
|
Related substances
|
Any impurity≤1.0%
|
0.26%
|
Dimethylaniline
|
≤20ppm
|
Complies (not used in process) |
Water
|
12.0%~15.0%
|
13.3%
|
Sulphated ash
|
≤0.5%
|
0.07%
|
Bulk density
|
0.45g/ml - 0.65g/ml
|
0.57g/ml
|
Tapped density
|
≥0.65g/ml
|
0.76g/ml
|
Assay
|
96.0%~102.0% C16H19N3O4S (calculated on the anhydrous basis) |
99.7%
|
Application
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