Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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This product is a macrolide antibiotic, which is the thiocyanate of erythromycin. This product is a veterinary drug, used for Gram-positive bacteria and mycoplasma infection; more as the initial raw material for the synthesis of erythromycin, roxithromycin, azithromycin, clarithromycin and other macrolide antibiotics.
Product Name
|
Erythromycin Thiocyanate |
CAS
|
7704-67-8 |
Appearance
|
White or almost white crystalline powder
|
MF
|
C37H67NO13.HCNS |
Molecular Weight
|
793.02 |
Purity
|
99% min
|
Storage
|
Keep in a cool, dry, dark location in a tightly sealed container or cylinder
|
Shelf Life
|
24 Months
|
Item
|
Standred
|
Results
|
Appearance
|
White or almost white crystalline powder
|
Almost white crystalline powder
|
Melting point
|
165-168°C
|
166-167°C
|
Identification
|
(1)The retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation,as obtained in the assay.
|
Complies
|
|
(2)UV absorption Max. at 266nm.
|
Complies
|
(3)IR spectra is consistent with CRS.
|
Complies
|
|
PH
|
6.0-8.0
|
7.6
|
Endotoxin |
0.33EU/mg max
|
Confirm
|
Related substances
|
Individual impurity not more than 0.5%
|
0.35%
|
Total impurities not more than 2.0%
|
0.76%
|
|
Loss on drying
|
≤6.0% |
3.25%
|
Residue on ignition
|
≤0.1% |
0.02%
|
Heavy metals
|
≤20ppm |
Confirms
|
Assay
|
98.5%min
|
99.3%
|
The antibacterial spectrum of erythromycin thiocyanate is similar to that of benzyl penicillin. It has a strong effect on Staphylococcus aureus, streptococcus and pneumococcus among gram-positive bacteria, and it has a strong effect on Pasteurella and Brucella among gram-negative bacteria. It also has a certain effect; in addition, this product is also effective against Mycoplasma, Rickettsia, Leptospira, Actinomyces, and Nocardia, but has no effect on intestinal negative bacilli such as Escherichia coli and Salmonella. Mainly used for severe infections caused by drug-resistant Staphylococcus aureus and hemolytic streptococcus, such as pneumonia, sepsis, endometritis, mastitis, etc.; for chronic respiratory diseases of poultry caused by mycoplasma, mycoplasma in pigs Pneumonia also has good curative effects, and it is also used for the treatment of nocardiasis in dogs and cats; it can also prevent whitehead white mouth disease of fry and fingerlings such as green, grass, silver carp, bighead carp, grass carp and herring bacterial gill rot, silver carp White skin disease in fish such as bighead carp and streptococcus disease in tilapia.
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