Manufacturer Supply Antifungal Raw Material 99% Terbinafine HCl CAS 78628-80-5

• Powder: Yes
• Customized: Customized
• Certification: GMP, HSE, ISO 9001, USP, BP
• Suitable for: Elderly, Children, Adult
• State: Solid
• Purity: >99%
• Model NO.: hd1059
• Assay: 99%
• CAS: 78628-80-5
• Mf: C21h26cln
• MW: 327.89
• Application: Antifungal
• Appearance: White or Almost White Crystalline Powder
• Certificate: ISO, GMP
• Test Method: HPLC
• Brand Name: Biohorlden
• Sample: Available
• Transport Package: 1kg/Bag, 25kg/Drum
• Specification: 99%
• Trademark: Biohorlden
• Origin: China
• HS Code: 29214990
• Production Capacity: 1000kg/Month

Product Description

Terbinafine hydrochloride is an antifungal, which is highly hydrophobic and tends to accumulate in hair, skin, nails, and fatty tissue.

Terbinafine hydrochloride is a white fine crystalline powder that is freely soluble in methano and dichloromethan, soluble in ethanol, and slightly soluble in water.

Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting squalene epoxidase, an enzyme that is part of the fungal cell membrane synthesis pathway. Because terbinafine prevents conversion of squalene to lanosterol, ergosterol cannot be synthesize.

 

Product Name	Terbinafine hydrochloride
CAS	78628-80-5
Appearance	White or almost white crystalline powder
MF	C21H26ClN
Molecular Weight	327.89
Purity	99% min
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder
Shelf Life	24 Months

Items of analysis	Specification	Results
Appearance	White or similar white powder, soluble in anhydrous ethanol and methano, slightly soluble in aceton, extremely soluble in water	Conforms
Identify	Comply with the standard	Conforms
Impurity B	≤0.15%	0.001%
Impurity E	≤0.05%	0.001%
Unknown single impurity	≤0.1%	0.03%
Total impurity	≤0.3%	0.1%
sulphated ash	≤0.1%	0.05%
Loss on dry	≤0.5%	0.2%
ignition residue	≤0.1%	0.021%
residual solvent	isopropano≤5000ppm;ethyl acetat≤5000ppm;trichloromethan≤60ppm	Isopropano 5ppm;ethyl acetat 101ppm;trichloromethan not detected
Assay	99-101%	99.7%

 

Terbinafine hydrochloride is a broad - spectrum antifungal drug for dermatology. It can specifically disrupt the late biological decomposition of sterols in fungi, selectively inhibit the activity of squalene cyclocyoxidase in fungi, and block the reaction of squalene epoxidation in the process of fungal cell membrane formation, so as to kill or inhibit fungi. Apply to treat skin candida disease, such as tinea pedis, tinea pedis, tinea cruris, tinea systemis and tinea versicolor, also be the best medicaments that treats fingernail at present.

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Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

1.Are you a manufacturer or trade company?

We are a professional manufacturer.

2.What's your payment terms?

Standard terms: T/T in advance and Western Union.

Also L/C at sight is acceptable for large amount.

3.What's your shipping time?

We have a large stock, which means we can deliver the goods to you immediately.

4.How do you ensure the quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

5.How do you ship the order normally?

For large qty order,ship the goods by sea.

For small qty order, by air or express. We supply optional express for you, including DHL,FEDEX,UPS,TXT,EMS,and so on.

6.What's your loading port?

Usually Shanghai, Qingdao, Tianjin, Guangzhou