| Customization: | Available |
|---|---|
| Powder: | Yes |
| Certification: | GMP, ISO 9001, USP, BP |
|
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| Product name:J-147 |
| Other Name: N-(2,4-DIMETHYLPHENYL)-N'-(3-METHOXYBENZYLIDENE)ACETOHYDRAZIDE |
| Appearance:White Powder |
| CAS:1146963-51-0 |
| M.F.:C18H17F3N2O2 |
| M.W.:350.33 |
| Specification:99% |
J 147 is a novel neurotrophic drug for cognitive enhancement and Alzheimer's disease. J 147 is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Application:
1.Applied in health product field;
2.Applied in medical field, J-147 has potential for the treatment of Alzheimer's disease (AD).
|
Product's Name
|
CAS
|
Purity
|
|
Nooglutyl
|
112193-35-8
|
99%
|
|
Noopept
|
157115-85-0
|
99%
|
|
Compound 7P
|
1890208-58-8
|
99%
|
|
Piracetam
|
7491-74-9
|
99%
|
|
Aniracetam
|
72432-10-1
|
99%
|
|
Nefiracetam
|
77191-36-7
|
99%
|
|
Pramiracetam
|
68497-62-1
|
99%
|
|
Oxiracetam
|
62613-82-5
|
99%
|
|
Fasoracetam
|
110958-19-5
|
99%
|
|
Sunifiram
|
314728-85-3
|
99%
|
|
Coluracetam
|
135463-81-9
|
99%
|
|
N-Methyl-D-aspartic acid(NMDA)
|
6384-92-5
|
99%
|
|
Alpha GPC(Choline Alfoscerate)
|
28319-77-9
|
99%
|
|
Alpha GPC(Choline Alfoscerate)
|
28319-77-9
|
50%
|
|
Citicoline
|
987-78-0
|
99%
|
|
Galantamine Hydrobromide
|
69353-21-5
|
99%
|
|
PRL-8-53
|
51352-87-5
|
99%
|
|
NSI-189 Phosphate
|
1270138-41-4
|
99%
|
|
NSI-189
|
1270138-40-3
|
99%
|
|
Tianeptine
|
66981-73-5
|
99%
|
|
Tianeptine sodium
|
30123-17-2
|
99%
|
|
Tianeptine hemisulfate monohydrate (THM)
|
1224690-84-9
|
99%
|
|
J-147
|
1146963-51-0
|
99%
|
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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