Customization: | Available |
---|---|
Powder: | Yes |
Customized: | Customized |
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Nystatin is a polyene antifungal drug to which many molds and yeast infections are sensitive, including Candida.Cutaneous, vaginal, mucosal and esophageal Candida infections usually respond well to treatment with nystatin.Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus.
Product Name
|
Nystatin |
CAS
|
1400-61-9 |
Appearance
|
Yellow powder |
MF
|
C47H75NO17 |
Molecular Weight
|
926.095 |
Purity
|
99%
|
Storage
|
Keep in a cool, dry, dark location in a tightly sealed container or cylinder
|
Shelf Life
|
24 Months
|
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Test items
|
Standard
|
Result
|
|
Description
|
Light yellow powder
|
Conforms
|
|
Identification |
IR
|
IR spectrum of sample is the same as working standard
|
Conforms
|
HPLC
|
HPLC RT of the sample is the same as the working standard
|
Conforms
|
|
Melting point
|
165.0°C~169.0°C
|
Conforms
|
|
Optical rotation
|
-23°~-29°
|
-27.4°
|
|
Loss on drying
|
NMT 1.0 %
|
0.17%
|
|
Residue on ignition
|
NMT 0.1 %
|
0.03%
|
|
Heavy metals
|
NMT 20ppm
|
Conforms
|
|
Related substances
|
|||
Impurity A
|
NMT 0.1 %
|
Not detected
|
|
Impurity B
|
NMT 0.1 %
|
Not detected
|
|
Impurity C
|
NMT 0.1 %
|
0.02%
|
|
Single impurity
|
NMT 0.2 %
|
0.17%
|
|
Total impurity
|
NMT 1.0 %
|
0.60%
|
|
Assay
|
NLT 99.0%
|
99.0%
|
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Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.