| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
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Pimobendan is a chemical drug used to treat mild, moderate or severe congestive heart failure caused by atrioventricular insufficiency or myocardial hypertrophy in dogs.
|
Product Name
|
Pimobendan |
|
CAS
|
74150-27-9 |
|
Appearance
|
White crystalline powder
|
|
MF
|
C19H18N4O2 |
|
Molecular Weight
|
334.37 |
|
Purity
|
99% min
|
|
Storage
|
Keep in a cool, dry, dark location in a tightly sealed container or cylinder
|
|
Shelf Life
|
24 Months
|
| Item | Specifications | Results |
| Appearance | White crystalline Powder | Confirms |
| solubility | Practically insoluble in water, freely soluble in dimethylformamide, slightly soluble in aceton and in methano. | Conforms |
| Identification | Infrared absorption spectrophotometry , Comparison pimobendan CRS | Conforms |
| Heavy metals | ≤10ppm | 1ppm |
| Water | ≤1.0% | 0. 1% |
| Assay (HPLC) | 98.0%~100.0% | 99.83% |
| Sulphated ash | ≤0.1% | 0.01% |
| Related substances(HPLC) | Impurity A:≤0.1% | 0.03% |
| Impurity B:≤0.1% | 0.07% | |
| Any other impurity:≤0.1% | 0.05% | |
| Total impurity:≤0.2% | 0.17% | |
| Conclusion | The results conforms with Enterprise standards |
Pimobendan is a cardiotonic agent. The study of the cardiotonic mechanism of pimobendan using ventricular muscles from rabbits and guinea pigs suggests that Pimobendan acts by inhibiting phosphodiesterase III and potassium channel. The potent venodilating action of pimobendan makes it a suitable treatment option for patients with congestive heart failure (CHF) as it also improves systemic vasoconstriction
Pimobendan is mainly used in the management of heart failure in dogs, most commonly caused by myxomatous mitral valve desease (also previously known as endocardiosis), ordilated cardiomyopathy.
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Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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