| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Non-Customized |
|
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Pharmaceutical Wholesale Price Chloroquine diphosphate cas 50-63-5high Purity Raw powder 99% chloroquine phosphate
| ommon Name | Chloroquine diphosphate | ||
|---|---|---|---|
| CAS Number | 50-63-5 | Molecular Weight | 515.862 |
| Density | N/A | Boiling Point | 460.6ºC at 760 mmHg |
| Molecular Formula | C18H32ClN3O8P2 | Melting Point | 200 °C (dec.)(lit.) |
| MSDS | ChineseUSA | Flash Point | 232.3ºC |
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TEM
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SPECIFICATION
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METHOD REFERENCE
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Appearance
|
white powder
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Visual
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|
Ammonium
|
≤200ppm
|
USPmonograph
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Chloride
|
≤200ppm
|
USP35<221>
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|
Sulfate
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≤300ppm
|
USP35<221>
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|
Iron
|
≤10ppm
|
USP35<241>
|
|
Arsenic
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≤2ppm
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USP35<211>
|
|
Heavy metals
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≤10ppm
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USP35<231>Method I
|
|
Loss on drying(3h at 105 ºC)
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≤0.5%
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USP35<731>
|
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Residue on Ignition
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≤0.1%
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USP35<281>
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Total impurities
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≤2.0%
|
USP monograph
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|
Assay(dry basis)
|
98.0% to 101.0%
|
USP monograph
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Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. ovale, and P. malariae. After the malaria parasite Plasmodium falciparum started to develop widespread resistance to it.
Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations.
In treatment of amoebic liver abscess, chloroquine may be used instead of or in addition to other medications in the event of failure of improvement with metronidazole or another nitroimidazole within 5 days or intolerance to metronidazole or a nitroimidazole.
As it mildly suppresses the immune system, it is used in some autoimmune disorders, such as rheumatoid arthritis and lupus erythematosus.
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