Customization: | Available |
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Powder: | Yes |
Customized: | Non-Customized |
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Product Name | Beclomethasone dipropionate |
Synonyms | 9-chloro-16-beta-methyl-11-beta,17,21-trihydroxy-pregna-1-4-diene-20-dione;beclacin; |
CAS | 5534-09-8 |
MF | C28H37ClO7 |
MW | 521.05 |
EINECS | 226-886-0 |
Product Categories | Active Pharmaceutical Ingredients; |
Items |
Specifications |
Results |
Appearance |
White to cream white, odorless powder |
White, odorless powder |
Identification (by IR) |
Conforms to the GRS spectrum |
+91.4° |
Loss on drying |
≤0.5% |
0.2% |
Sulphated ash |
≤0.1% |
0.09% |
Assay(by HPLC) |
97.0%~103.0% |
99.7% |
Related substances (by HPLC) |
Any individual impurity ≤1.5% Total impurities≤ 2.0% |
0.28% 0.62% |
Residual solvents |
Ethanol≤5000ppm Methylene chloride ≤600ppm Hexane ≤290ppm Dioxane ≤380ppm Pyridine ≤200ppm |
69ppm 43ppm Undetected (LOD 3ppm) Undetected(LOD 8pppm) Undetected (LOD 4ppm) |
Conclusion: meet the specification according to USP31. |
Function
1. It is highly effecitve glucosteroids.
2. No obvious influence on body temperature and micturition.
3. Effective on eczema, allergic dermatitis, neurodermitis, dermatitis contacta, psoriasis etc.
Application
1. renal cortex hormone, a potent topical corticosteroid drug, an anti-inflammatory, antiallergic and antipruritic effect, inhibits bronchial exudate, elimination of bronchial mucosal swelling, relieve bronchial spasm. Skin vasoconstriction effect far stronger than hydrocortisone hydrocortisone. Local anti-inflammatory effect was 5 times times the skin relaxed and ledercort. Lipophilic is strong, easy to penetrate, apply on the affected area take effect after 30 minutes.
2. also had no significant effect on temperature and urination. Thus, topical will not inhibit the human cortex and cortical dysfunction caused by adverse events. 3. topical treatment of inflammatory skin diseases such as eczema, atopic dermatitis, neurodermatitis, psoriasis, contact dermatitis, itching, etc. Aerosol can be used for chronic allergic rhinitis and allergic asthma, and so on.Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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