| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
|---|
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Pharmaceutical Raw Material Berberine Hydrochloride Powder Berberine HCl
| Product name:Berberine hydrochloride |
| Other Name:Berberine Hcl,Rhizoma Coptidis Extract |
| Appearance:Yellow Powder |
| CAS:633-65-8 |
| M.F:C20H18ClNO4 |
| M W:371.81 |
| Grade:Pharmaceutical Grade |
| Specification:99% |
Berberine Hydrochloride is an alkaloid derived from goldthread, bark of cork tree and other plants. It can be
also synthesized in artificial method. It is used as raw material to make preparations, which are usually
administered the treatment of intestinal infections and bacillary dysentery. Recently usage of anti-arrhythmic
was found .Berberine Hydrochloride has effect on intestinal infections, bacillary dysentery.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | Yellow powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
1. Removing heat and damp, relieving fire and eliminating toxins;
2.The antibacterial spectrum is wide, and it has antibacterial effect on a variety of gram-positive and nega
tive bacteria in vitro,among which it has antibacterial effect on hemolytic Streptococcus, Staphylococcus aureus
and Vibrio cholerae.
3.In vitro experiments have proved that berberine can enhance the phagocytosis of white blood cells and
hepatic reticular endothelial system.
4.With the function of relaxing vascular smooth muscle and exciting other smooth muscle, such as bladder muscle, bronchial muscle and gastrointestinal muscel.
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