Customization: | Available |
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Powder: | Yes |
Customized: | Customized |
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Product name:Orlistat |
Other Name:Orlistat Hcl |
Appearance:White Powder |
CAS:96829-58-2 |
M.F:C29H53NO5 |
M W:495.73 |
Grade:Pharmaceutical Grade |
Specification:99% |
Orlistat is designed to treat obesity. Its primary function is preventing the absorption of fats from the human diet, thereby reducing caloric intake. Orlistat works by inhibiting pancreatic lipase, an enzyme that breaks down triglycerides in the intestine.
Orlistat blocks some of the fat that you eat, keeping it from being absorbed by your body.
Orlistat is used to aid in weight loss, or to help reduce the risk of regaining weight already lost. This medicine must be used together with a reduced-calorie diet.
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ITEM | SPECIFICATION | RESULT | METHOD |
Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
Specific Optical | -2.4°~ -2.8° | -2.72° | |
Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
pH | 4.5~7.0 | 5.10 | |
Related substance | Spot not bigger than standard solution spot | No spot | TLC |
Water Content | ≤2% | 0.26% | KF |
Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Orlistat acts mainly on the gastrointestinal tract. It can inhibit the enzymes needed for digestion of fat in the gastrointestinal tract, including pancreatic and gastric esters, and reduce the absorption of fat by gastrointestinal esters to assist in weight loss.
Combined with a micro-low-energy diet for long-term treatment of obese and overweight people,including those who already have obesity-related risk factors. has the efficacy of long-term weight control (weight loss, maintenance and prevention of rebound).