| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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Pharmatical Grade 99% Purity Powder CAS 55 93-20-4 Be′tamethasone Dipropionate/Be′tamethasone 17, 21-Dipropionate
| Product name:Be′tamethasone Dipropionate |
| Other Name: Be'Tamethasone dipropionate/Be'Tamethasone 17,21-dipropionate |
| Appearance:White Powder |
| CAS:55 93-20-4 |
| M.F:C28H37FO7 |
| M W:504.59 |
| Grade:Pharmaceutical Grade |
| Specification:99% |
Be'Tamethasone dipropionate is a steroid ester that is Be'Tamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients. It has a role as an antipsoriatic. It is a steroid ester, an 11beta-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid, a propanoate ester and a 3-oxo-Delta(1),Delta(4)-steroid. It derives from a Be'Tamethasone.
Be'Tamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Be'Tamethasone dipropionate is a corticosteroid drug, sometimes called a steroid. Steroids reduce the amount of inflammatory chemicals your body makes. They also reduce your body's natural immune response, which helps to control inflammation.
Application:
Be'Tamethasone dipropionate is similar to the naturally occurring steroidal hormones produced by the adrenal glands. It is used to treat internal and external swelling associated with diseases like asthma, colitis, arthritis, severe skin allergies etc. It is also used for other conditions like adrenal hormonal insufficiency, certain types of anemia, cerebral edema etc.
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