| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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Supply 99% Purity Nad beta-Nicotinamide adenine dinucleotide disodium salt
| Product name:Beta-Nicotinamide adenine dinucleotide disodium salt |
| Other Name:Dihydronicotinamid-adenin-dinucleotid, Dinatriumsalz |
| Appearance:White Powder |
| CAS:606-68-8 |
| M.F:C21H30N7NaO14P2 |
| M.W.:689.44 |
| Specification:99% |
Nicotinamide adenine dinucleotide, abbreviated NADh+, is a coenzyme found in all living cells. The compound is a dinucleotide, since it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide.
In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another. The coenzyme is, therefore, found in two forms in cells: NAD+ is an oxidizing agent - it accepts electrons from other molecules and becomes reduced. This reaction forms NADH, (Nicotinamide adenine dinucleotide) which can then be used as a reducing agent to donate electrons. These electron transfer reactions are the main function of NAD+. However, it is also used in other cellular processes, the most notable one being a substrate of enzymes that add or remove chemical groups from proteins, in posttranslational modifications. Because of the importance of these functions, the enzymes involved in NAD+ metabolism are targets for drug discovery.
In organisms, NAD+ can be synthesized from simple building-blocks (de novo) from the amino acids tryptophan or aspartic acid. In an alternative fashion, more complex components of the coenzymes are taken up from food as the vitamin called niacin. Similar compounds are released by reactions that break down the structure of NAD+. These preformed components then pass through a salvage pathway that recycles them back into the active form. Some NAD+ is also converted into nicotinamide adenine dinucleotide phosphate (NADP+); the chemistry of this related coenzyme is similar to that of NAD+, but it has different roles in metabolism.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
NAD is useful for various life processes which are responsible for the proper maintenance and functioning of the body. Basically, it is used to generate energy in the body and to guard against many diseases.
1.Nicotinamide adenine dinucleotide (NAD) for Skincare: Being the highest coenzyme in metabolic process and the ability to repair damaged cells make NAD the most potent antioxidant. It helps in reducing the signs of aging and works as an essential element in skin care and provides energy to the aged and dead cells.
2.NAD in Cellular Respiration: NAD is an important enzyme in generating (Adenosine triphosphate) ATP which is the most important part of cellular respiration. Every cell in the body needs thousands of units of ATP and Nicotinamide adenine dinucleotide(NAD) helps in attaining this resource for the cells.
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