High Quality 99% Powder Hot Sale Nefazodone CAS 83366-66-9 Raw Powder High Purity 99% Nefazodone

• Powder: Yes
• Customized: Non-Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Elderly, Adult, Animal
• State: Solid
• Purity: >99%
• Model NO.: nefazodone
• Transport Package: 1kg Per Bag, 25kg Per Drum
• Specification: 99%
• Trademark: Biohorlden
• Origin: China
• Production Capacity: 50000kg/Month

Product Description

 

Product Description

High quality 99% powder Hot Sale nefazodone cas 83366-66-9 Raw powder high Purity 99% nefazodone

Common Name	nefazodone
CAS Number	83366-66-9	Molecular Weight	470.00700
Density	N/A	Boiling Point	N/A
Molecular Formula	C25H32ClN5O2	Melting Point	180-182°C

TEM	SPECIFICATION	METHOD REFERENCE
Appearance	white powder	Visual
Ammonium	≤200ppm	USPmonograph
Chloride	≤200ppm	USP35<221>
Sulfate	≤300ppm	USP35<221>
Iron	≤10ppm	USP35<241>
Arsenic	≤2ppm	USP35<211>
Heavy metals	≤10ppm	USP35<231>Method I
Loss on drying(3h at 105 ºC)	≤0.5%	USP35<731>
Residue on Ignition	≤0.1%	USP35<281>
Total impurities	≤2.0%	USP monograph
Assay(dry basis)	98.0% to 101.0%	USP monograph

Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant which was first marketed by Bristol-Myers Squibb in 1994 but has since largely been discontinued. BMS withdrew it from the market by 2004 due to decreasing sales due to the rare incidence of severe liver damage and the onset of generic competition. The incidence of severe liver damage is approximately 1 in every 250,000 to 300,000 patient-years. Generic versions were introduced in 2003.

Nefazodone is a phenylpiperazine compound and is related to trazodone. It has been described as a serotonin antagonist and reuptake inhibitor (SARI) due to its combined actions as a potent serotonin 5-HT2A receptor and 5-HT2C receptor antagonist and weak serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI).

Nefazodone is a potent inhibitor of CYP3A4, and may interact adversely with many commonly used medications that are metabolized by CYP3A4.

 

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Packaging & Shipping

Company Profile

Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

1.Are you a manufacturer or trade company?

We are a professional manufacturer.

2.What's your payment terms?

Standard terms: T/T in advance and Western Union.

Also L/C at sight is acceptable for large amount.

3.What's your shipping time?

3-5 days

4.How do you ensure the quality of your products?

Strict QC with 6 steps testing from raw material purchase to finished product.

5.How do you ship the order normally?

By air, by sea. By express: DHL,FEDEX,UPS,TXT,EMS,and so on.

6.What's your loading port?

Usually Beijing, Shanghai, Qingdao, Tianjin, Guangzhou