| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
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| Customization: |
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High Purity Raw Bisacodyl Powder For Constipation CAS 603-50-9 Bisacodyl
| Product name: Bisacodyl |
| Other Name:Durolax |
| Appearance:White powder |
| CAS:603-50-9 |
| M.F.:C22H19NO4 |
| M.W.:361.39 |
| Specification:99% |
Bisacodyl is a irritant laxative that mainly acts on the large intestine. After oral administration of bisacodyl, the products decomposed by intestinal bacteria and the drug itself have a strong stimulating effect on the intestinal wall, which can stimulate the sensory nerve endings to produce parasympathetic reflex, causing intestinal reflex peristalsis and leading to defecation. Bisacodyl can also stimulate local axon reflexes and segmental reflexes, and produce extensive colonic peristalsis. Therefore, bisacodyl may be effective for patients with ganglion blockage or spinal cord damage (paraplegia, polio). At the same time, bisacodyl can inhibit the absorption of sodium, chlorin and water in the colon, increase the volume of the intestine, and cause reflex defecation. Clinical application has confirmed that there is no damage to the heart, lung, liver, kidney, hematopoietic system and immune system after using bisacodyl.
| Product Name | CAS No. | Product Name | CAS No. |
| Lufenuron | 103055-07-8 | Toltrazuril | 69004-03-1 |
| Nitenpyram | 120738-89-8 | Praziquantel/Biltricide | 55268-74-1 |
| Fenbendazole | 43210-67-9 | Tetramisole Hcl | 5086-74-8 |
| Levamisole | 14769-73-4 | Ponazuril | 9004-4-2 |
| Diclazuril | 101831-37-2 | Florfenicol | 73231-34-2 |
| Ivermectin | 70288-86-7 | Enrofloxacin Hcl | 112732-17-9 |
| Albendazole | 54965-21-8 | Mebendazole | 31431-39-7 |
| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
Bisacodyl is a irritant laxative, which mainly acts on the large intestine and is clinically used for acute and chronic constipation. Suppository rectal medication can be used to clean the intestines before colonoscopy, intestinal X-ray examination or abdominal surgery.
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