| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, HSE, ISO 9001, USP, BP |
| Suitable for: | Elderly, Children, Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
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The antibacterial spectrum of Ceftriaxone sodium is similar to that of cefotaxime sodium. It has a powerful effect on Escherichia coli, Pneumoniae, Indole-positive Proteus, Influenzae, Serratia, Meningococcus, and Neisseria gonorrhoeae; Pneumococcus, Streptococcus and Staphylococcus aureus are moderately sensitive to this product
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Product Name
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Ceftriaxone sodium |
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CAS
|
74578-69-1 |
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Einecs No
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277-930-0 |
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Appearance
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White crystalline powder
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|
MF
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C18H17N8NaO7S3 |
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Molecular Weight
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576.562 |
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Purity
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99% min
|
|
Storage
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Keep in a cool, dry, dark location in a tightly sealed container or cylinder
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|
Shelf Life
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24 Months
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Item
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Specification
|
Results
|
||
|
Characters
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Appearance:almost white or yellowish, slightly hygroscopic, crystalline powder Solubility:freely soluble in water, sparingly soluble in methano, very slightly soluble in anhydrous ethanol. |
Almost white, slightly hygroscopic, crystalline powder; Solubility: Conform |
||
|
Identification
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1. A. Infrared absorption spectrophotometry, comparison; 2. B. It gives reaction (a) of sodium |
Positive
|
||
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PH
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6.0-8.0
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7.3
|
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|
Specific optical rotation
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-155°~-170°
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-160°
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Appearance of solution
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It is Clear and not more intensely colored than reference solution Y5 or BY5
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Clear,5
|
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Related substances
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Any impurity
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≤1.0%
|
0.1%
|
|
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Total impurities
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≤4.0%
|
0.4%
|
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Water
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≤8.0-11.0%
|
8.8%
|
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N,N-Dimethylanlline
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≤0.0020%
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Not detected
|
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2-Ethylhexanoic
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≤0.8%
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0.002%
|
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Bacterial endotoxins
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<0.08IU/mg
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<0.08IU/mg
|
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Sterility
|
Sterile
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Sterile
|
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Sub-visible particles
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≥10μm
|
Not more than 2250 particles/g
|
608 particles/g
|
|
|
≥25μm
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Not more than 225 particles/g
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26 particles/g
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Assay(based on anhydrous substance)
|
96.0%-102.0% of C18H16N8Na2O7S3
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99.2%
|
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Conclusion
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The above results meet the EP8.0th Edition
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|||
The antibacterial spectrum of Ceftriaxone sodium is similar to that of cefotaxime sodium. It is used for pneumonia, bronchitis, peritonitis, pleurisy caused by sensitive bacteria, and infections of skin and soft tissues, urinary tract, biliary tract, bone and joints, facial features, wounds, etc. It is also used for sepsis and meningitis.
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Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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