| Powder: | Yes |
|---|---|
| Customized: | Customized |
| Certification: | GMP, ISO 9001, USP, BP |
| Suitable for: | Adult |
| State: | Solid |
| Purity: | >99% |
| Samples: |
|---|
| Customization: |
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Pharmaceutical Chemical Raw Heparin Sodium Powder for Anticoagulation CAS 9041-08-1
| Product name:Heparin sodium |
| Other Name:Heparin sodium salt |
| Appearance:White Powder |
| CAS:9041-08-1 |
| M.F:(C12H16NS2Na3)20 |
| M W:0 |
| Grade:Pharmaceutical Grade |
| Specification:99% |
Heparin sodium interferes with many aspects of the blood coagulation process and has an anticoagulant effect both in vivo and in vitro.Its mechanism is complex, mainly through and antithrombin, and enhance the latter to activate the inhibitory effect of clotting factors and its consequences involved in preventing platelet aggregation and destruction, inhibit the formation of blood coagulation activation of enzyme, blocking prothrombin into thrombin, inhibition of thrombin, thereby preventing fibrinogen to fibrin,Thus play an anticoagulant role.
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| ITEM | SPECIFICATION | RESULT | METHOD |
| Appearance | White powder, neutral odor, highly hygroscopic | Conforms | Visual |
| Identification | Standard solution and test solution same spot,RF | Conforms | TLC |
| Specific Optical | -2.4°~ -2.8° | -2.72° | |
| Heavy metals (as PB) | ≤10ppm | Conforms | AAS |
| Sulfate (SO4) | ≤0.02% | Conforms | Colorimetry |
| Chloride (Cl) | ≤0.02% | Conforms | Colorimetry |
| Phosphate Ion (P) | ≤5ppm | Conforms | Colorimetry |
| Residual solvent(ethanol) | ≤1.0% | Conforms | HS-GC |
| pH | 4.5~7.0 | 5.10 | |
| Related substance | Spot not bigger than standard solution spot | No spot | TLC |
| Water Content | ≤2% | 0.26% | KF |
| Assay (dried basis) | 98.0%--102.0% | 99.48% | Potentiometric titration |
| Assay (dried basis) | 98.5%--100% | 99.2% | HPLC |
Function:
1. Prevent thrombosis and embolism, such as deep venous thrombosis, myocardial infarction, pulmonary embolism, thrombophlebitis and postoperative thrombosis, etc.
2. Treat disseminated intravascular coagulation (DIC) caused by various causes, such as bacterial sepsis, early placental dissection, and DIC caused by lysis of malignant tumor cells, except DIC caused by snakebite.Early application prevents the depletion of fibrinogen and other clotting factors.
3. Other anticoagulants in vivo and in vitro, such as cardiac catheterization, cardiopulmonary bypass, hemodialysis, etc.
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