Best Price Raw Material Chloramphenicol Powder CAS 56-75-7
Product name:Chloramphenicol |
Other Name: Chloramphenicol Hcl |
Appearance:White Powder |
CAS:56-75-7 |
M.F:C11H12Cl2N2O5 |
M W:323.13 |
Grade:Pharmaceutical Grade |
Specification:99% |
Chloramphenicol is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
Because of its excellent blood-brain barrier penetration (far superior to any of the cephalosporins), chloramphenicol remains the first-choice treatment for staphylococcal brain abscesses. It is also useful in the treatment of brain abscesses due to mixed organisms or when the causative organism is not known.
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Standards |
Results |
Physical Analysis |
|
|
Description |
White Powder |
Complies |
Assay |
99% |
99.6% |
Mesh Size |
100 % pass 80 mesh |
Complies |
Ash |
≤ 5.0% |
2.85% |
Loss on Drying |
≤ 5.0% |
2.65% |
Chemical Analysis |
|
|
Heavy Metal |
≤ 10.0 mg/kg |
Complies |
Pb |
≤ 2.0 mg/kg |
Complies |
As |
≤ 1.0 mg/kg |
Complies |
Hg |
≤ 0.1mg/kg |
Complies |
Microbiological Analysis |
|
|
Residue of Pesticide |
Negative |
Negative |
Total Plate Count |
≤ 1000cfu/g |
Complies |
Yeast&Mold |
≤ 100cfu/g |
Complies |
E.coil |
Negative |
Negative |
Salmonella |
Negative |
Negative |
Function:
Use of intravenous chloramphenicol has also been associated with gray baby syndrome, a phenomenon resulting from newborn infants' inability to metabolize chloramphenicol in the body. Other less serious reactions include fever, rashes, headache, and confusion. Prescription use is usually associated with monitoring of a patient's complete blood count. The drug should be discontinued upon appearance of reticulocytopenia, leukopenia, thrombocytopenia, anemia, or any other abnormal blood study findings attributable to chloramphenicol.
Although unpublished, recent research suggests chloramphenicol could also be applied to frogs to prevent their widespread destruction from fungal infections.It has recently been discovered to be a life-saving cure for chytridiomycosis in amphibians.
Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.
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