Pharmaceutical Chemical Powder CAS 81129-83-1 Cilastatin Sodium

• Powder: Yes
• Customized: Customized
• Certification: GMP, ISO 9001, USP, BP
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Model NO.: Biohorlden-H001
• Product Name: Cilastatin Sodium
• CAS: 81129-83-1
• Appearance: White Powder
• M.F.: C16h25n2o5s.Na
• M.W.: 380.44
• Shelf Life: 2 Years
• Storage: Room Temperature
• Grade: Medicine Grade
• Certificate: ISO/GMP
• Sample: Free Sample
• Transport Package: 10g/Bag; 100g/Bag; 1kg/Bag; 25kg/Bag
• Trademark: Biohorlden
• Origin: China
• HS Code: 2941906000
• Production Capacity: 500kg/Month

Product Description

Product Description

Pharmaceutical Chemical Powder CAS 81129-83-1 Cilastatin Sodium

 

Product name:Cilastatin sodium

Other Name:Cilastatin Sodium Salt

Appearance:White Powder

CAS:81129-83-1

M.F:C16H25N2O5S.Na

M W:380.44

Grade:Pharmaceutical Grade

Specification:99%

 

 The monosodium salt of cilastatin. It is an inhibitor of dehydropeptidase I (membrane dipeptidase, 3.4.13.19), an enzyme found in the brush border of renal tubes and responsible for degrading the antibiotic imipenem. Cilastatin sodium is therefore administ red with imipenem to prolong the antibacterial effect of the latter by preventing its renal metabolism to microbiologically inactive and potentially nephrotoxic products.
Biological ActivityDipeptidase inhibitor (LTDase, leukotriene D4 hydrolase, dehydropeptidase I) that displays a K i value of 0.11 μ M. Inhibits metabolism of LTD 4 to LTE 4 and the hydrolysis of β -lactam antibiotics. Nephroprotective; reduces toxic accumulation of cyclosporin A in kidney proximal tubule epithelial cells.

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Detailed Photos

Specification

tems	Standards	Results
Physical Analysis
Description	White Powder	Complies
Assay	99%	99.6%
Mesh Size	100 % pass 80 mesh	Complies
Ash	≤ 5.0%	2.85%
Loss on Drying	≤ 5.0%	2.65%
Chemical Analysis
Heavy Metal	≤ 10.0 mg/kg	Complies
Pb	≤ 2.0 mg/kg	Complies
As	≤ 1.0 mg/kg	Complies
Hg	≤ 0.1mg/kg	Complies
Microbiological Analysis
Residue of Pesticide	Negative	Negative
Total Plate Count	≤ 1000cfu/g	Complies
Yeast&Mold	≤ 100cfu/g	Complies
E.coil	Negative	Negative
Salmonella	Negative	Negative

 

Function&Application

Function:

Cilastatin sodium is particularly suitable for mixed infections caused by a variety of pathogens and aerobic/anaerobic bacteria, as well as early treatment before the pathogens are undetermined. This product is used for various infections caused by sensitive bacteria, especially suitable for multiple bacterial combined infections and mixed infections of aerobic and anaerobic bacteria, such as peritonitis, hepatobiliary infection, intra-abdominal abscess, appendicitis, gynecological infection, lower respiratory tract Infections, skin and soft tissue infections, urinary tract infections, bone and joint infections, and sepsis.

Company Profile

Xi'an Biohorlden Industry&Trade Co.,Ltd is a national key high-tech enterprise,which mainly specializes in the R&D, operation and production of pharmaceuticals,and intermediates.Our company is situated in E&T development zone,xi'an city shaanxi,it is easy of access. Our company has independent R&D center,raw material synthesis workshop, has advanced quality instruments and equipmentm,several product patents there are 15 experts in our research team.We insist in innovation and produce high quality products.

Certifications

Packaging & Shipping

 

FAQ

Q1: Are you a manufacturer?

Answer: Yes, we are manufactuer.

 

Q2: Which kind of payment terms do you accept?

Standard terms: T/T, MoneyGram, Western Union, PayPal.

Also L/C at sight is acceptable for large amount.

 

Q3: Can you give me a discount price?

Sure,It depends on your qty.

 

Q4: How can i get a sample?

Free samples are available for some products,but freight charges will be at your account and the charges will be return to you or deduct from your order in the future.

 

Q5: How to guarantee the Product Quality before placing orders?

Strict QC with 6 steps testing from raw material purchase to finished product.

 

Q6: How to solve the after-sale disputes?

First of all, our quality control will reduce the quality problem to near zero.

We accept Changing, Reshipping or Refunding service if any quality problem.